北京普华仕科技发展有限公司

 

马兜铃酸  Aristolochic acid

Reversible noncompetitive PLA₂  inhibitor.

Phospholipase A₂ (PLA₂) inhibitor active against the enzymes found in many snake venoms as well as those of human platelets and synovial fluids.  Inhibits ionophore-stimulated PLA₂ activity in human neutrophils. Has been shown to be nephropathic and carcinogenic.

PRODUCT PROPERTIES

Alternative Name:

8-Methoxy-6-nitrophenanthrol(3，4-d)-1，3-dioxide-5-carboxylic acid

MI:

14: 786

RTECS:

CF3325000

Source/Host:

Isolated from Aristolochia clematis.

Solubility:

Soluble in DMSO or 100% ethanol.

Long Term Storage:

+20°C

Hazard:

MAY BE CARCINOGENIC.
MAY BE MUTAGENIC.
TOXIC.

MW:

341.3

CAS:

313-67-7

Formula:

C₁₇H₁₁NO₇

Purity:

≥97% (~1:1 mixture of aristolochic acids I (A)  and II (B))

Appearance: